apalutamide will lower the level or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with prescription drugs which have been CYP3A4 substrates may lead to decreased publicity to these medicines.
Allergic reactions such as rash, angioedema, anaphylaxis, and Stevens–Johnson syndrome may possibly rarely be brought on by an immunological response to modafinil or its metabolites.
cenobamate will improve the stage or result of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Closely. Consider a dose reduction of CYP2C19 substrates, as clinically correct, when applied concomitantly with cenobamate.
Observe Closely (one)modafinil will raise the level or influence of diazepam intranasal by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep an eye on. Potent or reasonable CYP2C19 inhibitors may perhaps decrease fee of diazepam elimination, thereby rising adverse reactions to diazepam.
modafinil will lower the extent or impact of copyright topical by impacting hepatic enzyme CYP2B6 metabolism. Insignificant/Significance Not known.
Observe Carefully (one)voriconazole will enhance the stage or result of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Discontinue interfering medicines for at least five 50 percent-lives just before administration of possibly the dosimetry or an iobenguane dose. Never administer these drugs until eventually at the very least seven days soon after Just about every iobenguane dose.
Prevent driving and carrying out other responsibilities or actions that call for you to be inform right until the thing is how modafinil affects you. You may also have to have to stop undertaking these items if more info you do not really feel awake sufficient after using modafinil. If you still truly feel sleepy immediately after taking modafinil, speak with your doctor.
modafinil will enhance the stage or outcome of diazepam buccal by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep track of. Potent or reasonable CYP2C19 inhibitors may reduce charge of diazepam elimination, therefore raising adverse reactions to diazepam.
carbamazepine will reduce the extent or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Adhere to all directions with your prescription label. Usually do not just take this drugs in larger or smaller sized amounts or for longer than suggested.
Visit your medical professional or wellbeing treatment service provider for normal checks on your development. The full consequences of this medicine is probably not viewed without delay.
The presence of other professional medical challenges might have an effect on the use of this medication. Make sure you notify your physician When you've got every other health care issues, In particular:
Ensure you understand how you respond to this drugs before you travel, use equipment, or do other Work that require you to definitely be notify, properly-coordinated, or capable of Feel or see nicely.